Monday, April 7, 2025

Effects Of Alcohol On Brain And Mental Health

alcohol and depression brain

As traditional treatments often come with side effects or limited efficacy for some individuals, many are turning to natural supplements as complementary approaches to managing anxiety symptoms. “Recent studies have identified specific mechanisms by which alcohol alters gamma-aminobutyric acid (GABA) and glutamate systems, explaining why anxiety often worsens after drinking,” says White. She notes that alcohol is a depressant, and our body produces cortisol and adrenaline to counteract its effects. This means that as you sip to find relief from anxiety, you are actually reinforcing a loop that keeps you tethered to the emotions you’re trying to outrun.

The Relationship Between Depression and Alcohol: Facts and Statistics

The medications acamprosate, disulfiram, or naltrexone may also be used to help prevent further drinking. The advances made over these first 40 years have enriched understanding of alcoholism from a neuroscience perspective and have expanded concepts of neuroplasticity in the human brain. The innovations enabling discoveries also have generalized to other areas of neuroscience, exemplified by our understanding of neural degradation with chronic alcoholism and repair with sobriety. Original concepts of brain structure modification were unidirectional—that is, degradation occurred with age or disease without the chance of neuronal regeneration. Now, evidence supports the possibility of neurogenesis as part of a repair process (Nixon and Crews 2004) or at least for creating a milieu for repair of cell bodies and their processes. Repair of white matter constituents, including myelin, also can transpire.

alcohol and depression brain

Lifestyle and Behavior Changes

Some people may experience depressive symptoms in response to specific life stressors or events, such as grief, relationship difficulties, or job loss, which may not necessarily qualify as clinical depression but still warrant both attention and support. “Specifically, when you’re younger, your brain is going through a lot of changes. A huge risk factor for people who develop alcohol use disorder is early-onset drinking. So, if you drink before the age of 14, there’s about a 50% chance you’re going to develop an alcohol use disorder in your adulthood,” explains Dr. Anand.

Long-Term Effects of Alcohol on the Brain

Researchers found that those with an anxiety disorder were between 2.1 and 3.3 times as likely to develop alcohol use disorder. Many hangover symptoms arise due to detoxification, the physical process of ridding the body of toxic chemicals caused by alcohol consumption. Enzymes, mainly in the liver, metabolize (break down) alcohol, releasing a poisonous byproduct called acetaldehyde.

  • The most consistent results relate to manic episodes, wherein manic-depressive patients show a small but significant increased risk for alcoholism (Winokur et al. 1993).
  • However, this can lead to a vicious cycle where drinking exacerbates these issues, leading to more drinking as a means of temporary relief.
  • Alcohol abuse and dependence are both considered an alcohol use disorder, with studies finding that alcohol dependence is more closely tied to the persistence of depressive disorders.
  • There is a significant overlap between anxiety, alcohol misuse, and alcohol use disorder.
  • Reach out to a mental health professional to talk about treatment and strategies for dealing with depression.

Alcohol, even in small amounts, can elevate blood pressure and weaken the heart muscle, leading to increased risk of heart disease, stroke and heart failure over time, says Lacey Dunn, M.S., RD, a functional medicine dietitian. So, if you’ve been winding down with a glass of wine in hopes of protecting your heart, the latest research suggests it may be doing more harm than good. Many quality treatment programs also offer continuing linkage to your treatment providers and recovery community with aftercare programs, allowing you to stay connected and supported in your journey toward sustained recovery and better health. If you drink for long periods of time, it can cause depression, and when you abruptly stop drinking, it can cause anxiety,” says Dr. Anand.

Signs That Depression Is Taking a Toll on Your Relationship — and What to Do About It

She explains that alcohol reduces sleep quality by increasing nighttime awakenings and decreasing restorative sleep. White shares that newer research shows it also disrupts our slow-wave sleep, which is crucial for physical restoration and memory consolidation. Drinking may seem like a way to calm life’s storms, but it often adds more weight to the burdens we’re trying to lighten. “People often drink to cope with anxiety or depression, but alcohol actually disrupts our brain chemistry, making these conditions worse long-term,” says White. Depending on your individual needs, medication may also be recommended to help manage symptoms of depression and support your recovery from alcohol use disorder.

  • Poor or limited sleep causes grogginess and irritability, which can lead to feelings of depression or anxiety.
  • People who have difficulty clearing excess histamine might experience symptoms such as depression, anxiety, chronic nasal drip, asthma, sinus issues, bronchitis, eczema, rashes, swelling, allergies, insomnia, and digestive issues.
  • Some gut bacteria have been found to help convert tryptophan into serotonin, which can directly affect mood (39).
  • This speed–accuracy trade off may underlie performance deficits noted on timed tests, whether of a cognitive or motor nature.
  • After binge drinking, individuals often experience extreme mood swings, leading to feelings of guilt, shame, or sadness.

The Gut-Brain Axis: A Two-Way Street

alcohol and depression brain

Paradoxically, this psychoactive substance only exacerbates all these symptoms later on. Devineé Lingo is a registered dietitian nutritionist who is on a mission to cultivate health and wholeness in people seeking restoration and renewal. Her nutrition philosophy is to dig deeper and identify the root causes of people’s health concerns using a holistic, integrative and functional approach. Reaching out to your friends and family for support can provide invaluable encouragement and guidance. Involving your loved ones in your recovery process can strengthen your support network and foster a sense of connection and belonging, both of which are essential aspects Sobriety of the healing process.

Alcoholic hallucinosis

alcohol and depression brain

People may continue to drink partly to prevent or improve symptoms of withdrawal. After a person stops drinking alcohol, they may experience a low level of withdrawal lasting for months. Medically, alcoholism is considered both a physical and mental illness. Enrollment in a residential treatment program, also known as inpatient rehab, may be beneficial in addressing does alcohol make depression worse depression and substance abuse issues simultaneously.

alcohol and depression brain

Information on alcohol dependence

One prescient idea was that the primary breakdown product of alcohol, acetaldehyde, rather than the alcohol itself (i.e., ethanol), may have a key role in brain changes produced by chronic alcohol consumption. These ideas first were developed in a series of articles from the laboratory of Virginia Davis, including articles published in Science and Nature (Davis and Walsh 1970; Yamanaka et al. 1970). The idea that alcohol is only a “pro-drug” and that acetaldehyde is the effective agent has a boomerang quality because it is discarded every few years, only to return later.

Alcohol-Related Disorders

Variations in this gene might put people at risk of both alcohol misuse and depression. An alcohol-dependent person who demonstrates such psychological symptoms needs more intense intervention and support than may otherwise be provided, and if not appropriately treated, the symptoms may carry a worse prognosis for alcohol-related problems. High levels of depression are especially worthy of concern, because the risk of death by suicide among alcoholics, estimated to be 10 percent or higher, may be most acute during these depressed states. The aforementioned depressive disorders each have slightly different diagnostics criteria. The use of medication to treat an alcohol use disorder and a major depressive disorder depends entirely on the individual and their circumstances. A dual diagnosis can be complicated to treat, no matter the circumstances.

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Kayla Vincent
Kayla Vincent
Kayla Vincent is a word wizard and a caffeine connoisseur. She spends her days typing away on her keyboard, crafting captivating content and sipping on strong cups of coffee. When she's not blogging, you can find her exploring new brunch spots, browsing through antique shops, and spending quality time with her furry friend, Mr. Whiskers. Follow her blog for witty musings, lifestyle tips, and delicious brunch recommendations.

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